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Benzodiazepine drug
Cloniprazepam is a benzodiazepine derivative and a prodrug of clonazepam, 7-aminoclonazepam, and other metabolites.[1][2]
Some of the minor metabolites include 3-hydroxyclonazepam and 6-hydroxyclonazepam, 3-hydroxycloniprazepam and ketocloniprazepam with ketone group formed where 3-hydroxy group was.[1]
It is a designer drug and an NPS (short for "new psychoactive substance").[1] At the end of 2017, cloniprazepam was an uncontrolled substance in most of the countries.
See also
- Flutoprazepam
- Ro05-4082
- List of designer drugs
- List of benzodiazepines
- List of benzodiazepine designer drugs
References
- ^ a b c Moosmann B, Bisel P, Franz F, Huppertz LM, Auwärter V (November 2016). "Characterization and in vitro phase I microsomal metabolism of designer benzodiazepines - an update comprising adinazolam, cloniprazepam, fonazepam, 3-hydroxyphenazepam, metizolam and nitrazolam". Journal of Mass Spectrometry. 51 (11): 1080–1089. Bibcode:2016JMSp...51.1080M. doi:10.1002/jms.3840. PMID 27535017.
- ^ Mortelé O, Vervliet P, Gys C, Degreef M, Cuykx M, Maudens K, et al. (May 2018). "In vitro Phase I and Phase II metabolism of the new designer benzodiazepine cloniprazepam using liquid chromatography coupled to quadrupole time-of-flight mass spectrometry". Journal of Pharmaceutical and Biomedical Analysis. 153: 158–167. doi:10.1016/j.jpba.2018.02.032. hdl:10067/1496330151162165141. PMID 29494888. S2CID 3946404.
External links
- https://www.unodc.org/LSS/Substance/Details/d115de07-ab8f-4454-a8f7-3ea15f4a0748
- https://web.archive.org/web/20160623204002/http://nsddb.eu/substance/590/
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