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Chamazulene is an aromatic chemical compound with the molecular formula C14H16 found in a variety of plants including in chamomile (Matricaria chamomilla), wormwood (Artemisia absinthium), and yarrow (Achillea millefolium).[1] It is a blue-violet derivative of azulene which is biosynthesized from the sesquiterpene matricin.[2]
Biosynthesis of chamazulene (3) from matricin (1) via a carboxylic acid of chamazulene (2).
Chamazulene has anti-inflammatory properties in vivo and inhibits the CYP1A2 enzyme.[2]
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