Broflanilide is a complex, polycyclic, organohalogen insecticide which provides a novel mode of action (MoA).

Mode of action

Upon its discovery by Mitsui Chemicals, Insecticide Resistance Action Committee (IRAC) created the new MoA Group 30 for Broflanilide.[1][2][3][4] Broflanilide is a meta-diamide GABA-gated Cl− channel allosteric modulator.[1][2][3][4] This - along with isoxazolines providing the same MoA, so far only fluxametamide - constitute the new MoA Group 30 in the IRAC classification scheme.[3]

Advantages

Environmental Hazards

The EPA has stated that Broflanilide is "Likely to be Carcinogenic to Humans".[5]

Broflanilide meets the EPA Working Definition of PFAS. Note that "EPA considers any level of PFAS to be potentially toxicologically significant".[6]

Products

Products were registered in the United States in January, 2021,[7] and in Canada.[1] It is being sold under the brand names Cimegra (BASF)[8] and Teraxxa (BASF, the seed treatment form).[9]

References

  1. ^ a b c d BASF AgSolutions CA (Feb 16, 2021). Wireworm Manamgent Strategies. Youtube. Canada.
  2. ^ a b IRAC Mode of Action Classification, Annex 6, 2018
  3. ^ a b c "IRAC Mode of Action Classification Scheme Version 9.4". IRAC (Insecticide Resistance Action Committee) (pdf). March 2020.
  4. ^ a b Katsuta, Hiroyuki; Nomura, Michikazu; Wakita, Takeo; Daido, Hidenori; Kobayashi, Yumi; Kawahara, Atsuko; Banba, Shinichi (2019-05-20). "Discovery of broflanilide, a novel insecticide". Journal of Pesticide Science. 44 (2). Pesticide Science Society of Japan: 120–128. doi:10.1584/jpestics.d18-088. ISSN 1348-589X. PMC 6529746. PMID 31148938. S2CID 133133494.
  5. ^ "Broflanilide; Pesticide Tolerances". EPA. Retrieved 16 November 2021.
  6. ^ "Per- and Polyfluoroalkyl Substances (PFAS) in Pesticide Packaging". EPA. 13 January 2021. Retrieved 15 November 2021.
  7. ^ "New Active Ingredient Broflanilide". EPA. Retrieved 16 November 2021.
  8. ^ "Cimegra® - Product Profile". BASF Agriculture Western Canada. BASF Canada. 2021-03-10. Retrieved 2021-03-10.
  9. ^ "Teraxxa™ and Teraxxa™ F4 Seed Treatments". BASF Agriculture US. BASF US. Retrieved 2021-03-10.