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Chemical compound
Bencyclane is an antispasmodic, vasodilator, and platelet aggregation inhibitor.[1]
Synthesis
Grignard addition of benzylmagnesiumbromide to suberone would give 1-benzylcycloheptanol [4006-73-9] (1'). Williamson ether synthesis with 3-dimethylaminopropylchloride [109-54-6] (2) completed the synthesis of bencyclane (3).
See also
References
- ^ J. Elks, ed. (2014). The Dictionary of Drugs: Chemical Data, Structures and Bibliographies. Springer.
- ^ Pallos, L.; Budai, Z.; Zólyomi, G. (1972). "Basic ethers of 1-substituted cycloalkanols. 1". Arzneimittel-Forschung. 22 (9): 1502–1505. PMID 4678613.
- ^ Pallos, L.; Budai, Z.; Zólyomi, G. (1972). "Basic ethers of 1-substituted cycloalkanols. 2". Arzneimittel-Forschung. 22 (9): 1505–1509. PMID 4678614.
- ^ Anon., ES 376120 (1972-04-01 to Gallardo Antonio SA).
- ^ Spaeter Genannt Werden Wird, DE 2455051A1 (1975 to Andreu S A Lab).
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