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Aspalathin is a C-linked dihydrochalcone glucoside found in rooibos tea, a herbal tea prepared from the South African rooibos plant, Aspalathus linearis (Fabaceae).[1]

It was first isolated in 1965 by chromatography.[2]

It has demonstrated antidiabetic activity.[3]

References

  1. ^ Bramati L; et al. (2002). "Quantitative Characterization of Flavonoid Compounds in Rooibos Tea (Aspalathus linearis) by LC-UV/DAD". Journal of Agricultural and Food Chemistry. 50 (20). Elsevier: 5513–5519. doi:10.1021/jf025697h. PMID 12236672.
  2. ^ Koeppen, B. H.; Roux, D. G. (June 1966). "C-Glycosylflavonoids. The chemistry of aspalathin". Biochemical Journal. 99 (3): 604–609. doi:10.1042/bj0990604. ISSN 0264-6021. PMC 1265048. PMID 4290475.
  3. ^ Bader, Michael; Mazibuko-Mbeje, Sithandiwe E.; Dludla, Phiwayinkosi V.; Johnson, Rabia; Joubert, Elizabeth; Louw, Johan; Ziqubu, Khanyisani; Tiano, Luca; Silvestri, Sonia; Orlando, Patrick; Opoku, Andy R.; Muller, Christo J. F. (2019). "Aspalathin, a natural product with the potential to reverse hepatic insulin resistance by improving energy metabolism and mitochondrial respiration". PLOS ONE. 14 (5): e0216172. Bibcode:2019PLoSO..1416172M. doi:10.1371/journal.pone.0216172. ISSN 1932-6203. PMC 6497260. PMID 31048842.

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