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Arthur Guinness (1725–1803) was an Irish entrepreneur who founded the Guinness Brewery.

Arthur Guinness may also refer to:

• The Second Arthur Guinness (1768–1855), Dublin brewer and banker, father of Benjamin Guinness
• Arthur Guinness, 1st Baron Ardilaun (1840–1915), Irish businessman, politician, and philanthropist
• Arthur C. C. J. Guinness (1841–1897), a son of Richard Samuel Guinness
• Arthur Guinness (New Zealand politician) (1846–1913), Member of Parliament
• Arthur Guinness, 4th Earl of Iveagh (born 1969)