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The enzyme retinoid isomerohydrolase (EC 3.1.1.64, all-trans-retinyl-palmitate hydrolase) catalyzes the reaction
- an all-trans-retinyl ester + H2O = 11-cis-retinol + a fatty acid
This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is all-trans-retinyl ester acylhydrolase, 11-cis retinol-forming. This enzyme participates in retinol metabolism.
References
- Blaner WS, Das SR, Gouras P, Flood MT (1987). "Hydrolysis of 11-cis- and all-trans-retinyl palmitate by homogenates of human retinal epithelial cells". J. Biol. Chem. 262 (1): 53–8. PMID 3793734.
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