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The enzyme actinomycin lactonase (EC 3.1.1.39) catalyzes the reaction

actinomycin + H₂O

\rightleftharpoons

actinomycinic monolactone

This enzyme belongs to the family of hydrolases, specifically those acting on carboxylic ester bonds. The systematic name is actinomycin lactonohydrolase.

References

Hou CT, Perlman D (1970). "Microbial transformations of peptide antibiotics. V. Purification and properties of the actinomycin lactonase from Actinoplanes missouriensis". J. Biol. Chem. 245 (6): 1289–95. PMID 4191854.

Enzymes
Activity	Active site Binding site Catalytic triad Oxyanion hole Enzyme promiscuity Diffusion-limited enzyme Cofactor Enzyme catalysis
Regulation	Allosteric regulation Cooperativity Enzyme inhibitor Enzyme activator
Classification	EC number Enzyme superfamily Enzyme family List of enzymes
Kinetics	Enzyme kinetics Eadie–Hofstee diagram Hanes–Woolf plot Lineweaver–Burk plot Michaelis–Menten kinetics
Types	EC1 Oxidoreductases (list) EC2 Transferases (list) EC3 Hydrolases (list) EC4 Lyases (list) EC5 Isomerases (list) EC6 Ligases (list) EC7 Translocases (list)

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References

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