How Can We Help?
You are here:
< Back
Stimulant designer drug
4-Methylcathinone (also known as Nor-Mephedrone, 4-MC and NSC-60487), is a stimulant drug of the cathinone chemical class. It is a metabolite of the better known drug mephedrone (4-methylmethcathinone).[1][2][3][4]
4-Methylcathinone displays a 2.4-fold selectivity to promote monoamine release via DAT over SERT as opposed to 309-fold selectivity for cathinone.[5]
See also
References
- ^ "nor-Mephedrone". Cayman Chemical. Retrieved 27 June 2015.
- ^ Meyer MR, Wilhelm J, Peters FT, Maurer HH (June 2010). "Beta-keto amphetamines: studies on the metabolism of the designer drug mephedrone and toxicological detection of mephedrone, butylone, and methylone in urine using gas chromatography-mass spectrometry". Analytical and Bioanalytical Chemistry. 397 (3): 1225–33. doi:10.1007/s00216-010-3636-5. PMID 20333362. S2CID 21471611.
- ^ Pedersen AJ, Reitzel LA, Johansen SS, Linnet K (June 2013). "In vitro metabolism studies on mephedrone and analysis of forensic cases". Drug Testing and Analysis. 5 (6): 430–8. doi:10.1002/dta.1369. PMID 22573603.
- ^ Dargan PI, Sedefov R, Gallegos A, Wood DM (July–August 2011). "The pharmacology and toxicology of the synthetic cathinone mephedrone (4-methylmethcathinone)". Drug Testing and Analysis. 3 (7–8): 454–63. doi:10.1002/dta.312. PMID 21755604.
- ^ Hutsell BA, Baumann MH, Partilla JS, Banks ML, Vekariya R, Glennon RA, Negus SS (February 2016). "Abuse-related neurochemical and behavioral effects of cathinone and 4-methylcathinone stereoisomers in rats". European Neuropsychopharmacology. 26 (2): 288–297. doi:10.1016/j.euroneuro.2015.12.010. PMC 5331761. PMID 26738428.
Phenylalkyl- amines (other than cathinones) |
|
---|---|
Cyclized phenyl- alkylamines | |
Cathinones | |
Tryptamines | |
Chemical classes |
Categories
-
Annuals36
-
Bulbs, Corms & Tubers41
-
Ferns27
-
Fruits3
-
Garden Plants23
-
Grasses26
-
Herb17
-
Insects1
-
Mammals1
-
Midwest Native Plants0
-
Northeast Native Plants112
-
Perennials123
-
Rose1
-
Shrubs47
-
Trees112
-
Tropical Plants53
-
Upland Birds5
-
Vines18
-
Viola Tricolor1
-
Water Gardening & Plants9
-
Waterfowl0
-
Wetland Birds0
-
Wetland Plants4
-
Wildbirds172
-
Wildflowers1
-
Woodland Plants29
Table of Contents
Recent Comments