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by | Mar 16, 2018 | Hosta

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3-Deoxy-d-manno-oct-2-ulosonic acid (ketodeoxyoctonic acid; KDO; IUPAC symbol Kdo) is an ulosonic acid of a 2-ketooctose which is used by bacteria in the synthesis of lipopolysaccharides.[1] The d-manno prefix indicates that the four chiral centers have the same configuration as d-mannose.

The cyclization of 3-deoxy-d-manno-oct-2-ulosonic acid to the β-anomer. The chiral centers are indicated by asterisks.

References

  1. ^ Ghalambor, Mohammad Ali; Levine, Edward M.; Heath, Edward C. (1966). "The biosynthesis of cell wall lipopolysaccharide in Escherichia coli. III. The isolation and characterization of 3-deoxyoctulosonic acid". Journal of Biological Chemistry. 241 (13): 3207–15. doi:10.1016/S0021-9258(18)96516-6. PMID 4287911.


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