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2-oxoglutaramate amidase (EC 3.5.1.111, omega-amidase) is an enzyme with systematic name 5-amino-2,5-dioxopentanoate amidohydrolase.[1] This enzyme catalyses the following chemical reaction
- 2-oxoglutaramate + H2O 2-oxoglutarate + ammonia
The enzyme participates in the nicotine degradation pathway of several Gram-positive bacteria.
References
- ^ Cobzaru C, Ganas P, Mihasan M, Schleberger P, Brandsch R (April 2011). "Homologous gene clusters of nicotine catabolism, including a new ω-amidase for α-ketoglutaramate, in species of three genera of Gram-positive bacteria". Research in Microbiology. 162 (3): 285–91. doi:10.1016/j.resmic.2011.01.001. PMID 21288482.
External links
- 2-oxoglutaramate+amidase at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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