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2-C-Methyl-D-erythritol 4-phosphate (MEP) is an intermediate on the MEP pathway (non-mevalonate pathway) of isoprenoid precursor biosynthesis.[1] It is the first committed metabolite on that pathway on the route to IPP and DMAPP.
See also
- DXP reductoisomerase
- MEP pathway (formerly known as the non-mevalonate pathway)
- Fosmidomycin
References
- ^ Takahashi S, Kuzuyama T, Watanabe H, Seto H (1998). "A 1-deoxy-D-xylulose 5-phosphate reductoisomerase catalyzing the formation of 2-C-methyl-D-erythritol 4-phosphate in an alternative nonmevalonate pathway for terpenoid biosynthesis". Proc. Natl. Acad. Sci. U.S.A. 95 (17): 9879–84. Bibcode:1998PNAS...95.9879T. doi:10.1073/pnas.95.17.9879. PMC 21430. PMID 9707569.
External links
- 2-C-methylerythritol+4-phosphate at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
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