Hosta

15α-Hydroxyestradiol (15α-OH-E2) is an endogenous estrogen which occurs during pregnancy.^[1]^[2]^[3] It is structurally related to estriol (16α-hydroxyestradiol) and estetrol (15α-hydroxyestriol or 15α,16α-dihydroxyestradiol).

References

^ Lisboa BP, Goebelsmann U, Diczfalusy E (March 1967). "Isolation of 15-alpha-hydroxyoestradiol from human pregnancy urine". Acta Endocrinol. 54 (3): 467–72. doi:10.1530/acta.0.0540467. PMID 6071364.
^ Jirku H, Kadner S, Levitz M (October 1972). "Metabolism of 15alpha-hydroxyestradiol in human pregnancy". J. Clin. Endocrinol. Metab. 35 (4): 522–34. doi:10.1210/jcem-35-4-522. PMID 4559652.
^ Lee AJ, Kosh JW, Conney AH, Zhu BT (August 2001). "Characterization of the NADPH-dependent metabolism of 17beta-estradiol to multiple metabolites by human liver microsomes and selectively expressed human cytochrome P450 3A4 and 3A5". J. Pharmacol. Exp. Ther. 298 (2): 420–32. PMID 11454902.

[pmid6071364-1] Lisboa BP, Goebelsmann U, Diczfalusy E (March 1967). "Isolation of 15-alpha-hydroxyoestradiol from human pregnancy urine". Acta Endocrinol. 54 (3): 467–72. doi:10.1530/acta.0.0540467. PMID 6071364.

[pmid4559652-2] Jirku H, Kadner S, Levitz M (October 1972). "Metabolism of 15alpha-hydroxyestradiol in human pregnancy". J. Clin. Endocrinol. Metab. 35 (4): 522–34. doi:10.1210/jcem-35-4-522. PMID 4559652.

[pmid11454902-3] Lee AJ, Kosh JW, Conney AH, Zhu BT (August 2001). "Characterization of the NADPH-dependent metabolism of 17beta-estradiol to multiple metabolites by human liver microsomes and selectively expressed human cytochrome P450 3A4 and 3A5". J. Pharmacol. Exp. Ther. 298 (2): 420–32. PMID 11454902.

[1]

[2]

[3]

Hosta

References

Recent Comments