Galax

by | Mar 29, 2018 | Galax

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ADDA ((all-S,all-E)-3-amino-9-methoxy-2,6,8-trimethyl-10-phenyldeca-4,6-dienoic acid) is a non-proteinogenic amino acid found in toxins made by cyanobacteria. Toxins which include this amino acid include microcystins[1] and nodularins.

Along with leucine and arginine, it is found in microcystin-LR, an extremely toxic compound produced by cyanobacteria. In order to treat a water supply contaminated with microcystin-LR, chlorination can be used to oxidize the double bonds of ADDA in order to initiate the chemical breakdown of this compound.[2]

References

  1. ^ Rudolph-Böhner, Sabine; Mierke, Dale F.; Moroder, Luis (1994). "Molecular structure of the cyanobacterial tumor-promoting microcystins". FEBS Letters. 349 (3): 319–323. doi:10.1016/0014-5793(94)00680-6. PMID 8050589. S2CID 23312111.
  2. ^ "ADDA". American Chemical Society. Retrieved 5 February 2023.
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