Flame Azalea – Rhododendron calendulaceum

by | Dec 19, 2023 | Azalea

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Kallidin is a bioactive kinin formed in response to injury from kininogen precursors through the action of kallikreins.[1]

Kallidin is a decapeptide whose sequence is H-Lys-Arg-Pro-Pro-Gly-Phe-Ser-Pro-Phe-Arg-OH. It can be converted to bradykinin by the aminopeptidase enzyme.

It can be a substrate for carboxypeptidase M and N.[2]

Kallidin is identical to bradykinin with an additional lysine residue added at the N-terminal end and signals through the bradykinin receptor.

References

  1. ^ Campbell, Duncan John (2013). "Chapter 188 - Bradykinin Peptides". In Kastin, Abba J. (ed.). Handbook of Biologically Active Peptides (2nd ed.). Elsevier. doi:10.1016/C2010-0-66490-X. ISBN 978-0-12-385095-9 – via ScienceDirect.
  2. ^ Stefan Offermanns; Walter Rosenthal (2008). Encyclopedia of Molecular Pharmacology. Springer. pp. 673–. ISBN 978-3-540-38916-3. Retrieved 11 December 2010.


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