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Clotizolam (Ro11-1465) is a thienotriazolodiazepine derivative first invented in the 1970s, which in more recent years has been sold as a designer drug. As with other related thienotriazolodiazepines, it produces sedative, anxiolytic, anticonvulsant and muscle relaxant effects,[1] and also acts as an inhibitor of platelet-activating factor (PAF).[2]

See also

References

  1. ^ US 4155913, Hellerbach J, Zeller P, Binder D, Hromatka O, "Thienotriazolodiazepine derivatives", issued 22 May 1979, assigned to Hoffmann La Roche Inc. 
  2. ^ Tahara T, Mikashima H, Terasawa M, Maruyama Y (May 1987). "PAF antagonistic activity of some thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepines". Chemical & Pharmaceutical Bulletin. 35 (5): 2119–21. doi:10.1248/cpb.35.2119. PMID 3664818. S2CID 27564672.


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