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Acetoxolutamide is a nonsteroidal androgen and selective androgen receptor modulator (SARM) which was described in 2000 and was never developed or marketed for medical use.[1] It was derived from structural modification of the nonsteroidal antiandrogen bicalutamide and the nonsteroidal SARM acetothiolutamide.[1] Acetoxolutamide shows greatly improved pharmacokinetic properties and anabolic and androgenic potency relative to acetothiolutamide in animals.[1] It is the (2R) enantiomer of andarine (also known as acetamidoxolutamide or androxolutamide).[1]

References

  1. ^ a b c d Yin D (December 2000). Pharmacology, Pharmacokinetics and Metabolism of Nonsteroidal Androgens (Ph.D. thesis). The University of Tennessee Health Science Center. ProQuest 304669272.



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