Fragile Fern – Cystopteris fragilis

by | Dec 9, 2023 | Ferns, NE Native Ferns

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Josamycin is a macrolide antibiotic. It was isolated by Hamao Umezawa and his colleagues from strains of Streptomyces narbonensis var. josamyceticus var. nova in 1964.[1][2]

It is currently sold in various countries.Brand examples are:

  • Europe: Josalid, Josacine, Iosalide, Josamina
  • Russia: Wilprafen (Вильпрафен)
  • Japan: Josamy

Adverse effects

There has been a case report of edema of the feet.[3]

References

  1. ^ Osono T, Oka Y, Watanabe S, Okami Y, Umezawa H (July 1967). "A new antibiotic, josamyicn. I. Isolation and physico-chemical characteristics". The Journal of Antibiotics. 20 (3): 174–180. PMID 6072798.
  2. ^ Umezawa H (1982). "Discovery of josamycin". Giornale Italiano di Chemioterapia. 29 (Suppl 1): 1–10. PMID 6765367.
  3. ^ Bosch X, Pedrol E, Casado X, Urbano-Marquez A (July 1993). "Josamycin-induced pedal oedema". BMJ. 307 (6895): 26. doi:10.1136/bmj.307.6895.26-a. PMC 1678472. PMID 8343666.
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