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Defending champions Esther Vergeer and Sharon Walraven defeated Jiske Griffioen and Aniek van Koot in the final, 7–5, 6–7(8–10), 6–4 to win the women's doubles wheelchair tennis title at the 2011 US Open. With the win, they completed the Grand Slam.
Seeds
Esther Vergeer / Sharon Walraven (champions)- Jiske Griffioen / Aniek van Koot (final)
Doubles
Key
- Q = Qualifier
- WC = Wild card
- LL = Lucky loser
- Alt = Alternate
- SE = Special exempt
- PR = Protected ranking
- ITF = ITF entry
- JE = Junior exempt
- w/o = Walkover
- r = Retired
- d = Defaulted
- SR = Special ranking
Finals
| Semifinals | Finals | ||||||||||||
| 1 | Esther Vergeer Sharon Walraven
| 6 | 7 | ||||||||||
 Daniela di Toro Emmy Kaiser
| 2 | 5 | |||||||||||
| 1 | Esther Vergeer Sharon Walraven
| 7 | 68 | 6 | |||||||||
| 2 | Jiske Griffioen Aniek van Koot
| 5 | 710 | 4 | |||||||||
Marjolein Buis Annick Sevenans
| 4 | 68 | |||||||||||
| 2 | Jiske Griffioen Aniek van Koot
| 6 | 710 | ||||||||||
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