Chionodoxa

by | Mar 12, 2018 | Chionodoxa

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Pinoxepin (INNTooltip International Nonproprietary Name; developmental code name P-5227; pinoxepin hydrochloride (USANTooltip United States Adopted Name)) is an antipsychotic of the tricyclic group with a dibenzoxepin ring system which was developed in the 1960s but was never marketed.[1][2][3][4][5] It was found in clinical trials to have effectiveness in the treatment of schizophrenia similar to that of chlorpromazine and thioridazine.[4] The drug has marked sedative effects but causes relatively mild extrapyramidal symptoms.[2][4]

References

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 984–. ISBN 978-1-4757-2085-3.
  2. ^ a b Annual Reports in Medicinal Chemistry. Academic Press. 1 January 1967. pp. 2–. ISBN 978-0-08-058346-4.
  3. ^ Gordon M (2 December 2012). Psychopharmacological Agents. Elsevier Science. pp. 102–. ISBN 978-0-323-15128-3.
  4. ^ a b c Iversen L (6 December 2012). Handbook of Psychopharmacology: Volume 10: Neoroleptics and Schizophrenia. Springer Science & Business Media. pp. 200–. ISBN 978-1-4613-4042-3.
  5. ^ Lajtha A (11 November 2013). Alterations of Metabolites in the Nervous System. Springer Science & Business Media. pp. 335–. ISBN 978-1-4757-6740-7.



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