Cedrus Deodara

by | Mar 20, 2018 | Cedrus Deodara

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Prolame, also known as 17β-((3-hydroxypropyl)amino)estradiol, is a synthetic, steroidal estrogen and a 17β-aminoestrogen with anticoagulant effects that was first described in 1985 but was never marketed.[1][2][3][4][5]

References

  1. ^ J. Elks (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 1025–. ISBN 978-1-4757-2085-3.
  2. ^ Fernández JM, Rubio-Arroyo MF, Soriano-García M, Toscano RA, Pérez-César MC (1985). "Synthesis and molecular structure of prolame, N-(3-hydroxy-1,3,5(10)-estratrien-17 beta-yl)-3-hydroxypropylamine; an amino-estrogen with prolonged anticoagulant and brief estrogenic effects". Steroids. 45 (2): 151–7. doi:10.1016/0039-128x(85)90044-3. PMID 3841424. S2CID 45993880.
  3. ^ Rubio-Póo C, Mandoki JJ, Mendoza-Patiño N, Lemini C, de la Peña A, Cruz F, Zavala E, Silva G, Garcia-Mondragón J, Fernández JM (1985). "The anticoagulant effect of prolame, N-(3-hydroxy-1,3,5(10)estratrien-17 beta-yl)-3-hydroxypropylamine, a novel amino-estrogen". Steroids. 45 (2): 159–70. doi:10.1016/0039-128x(85)90045-5. PMID 3841425. S2CID 24724648.
  4. ^ Jaimez R, Cooney A, Jackson K, Lemus AE, Lemini C, Cárdenas M, García R, Silva G, Larrea F (2000). "In vivo estrogen bioactivities and in vitro estrogen receptor binding and transcriptional activities of anticoagulant synthetic 17beta-aminoestrogens". J. Steroid Biochem. Mol. Biol. 73 (1–2): 59–66. doi:10.1016/s0960-0760(00)00053-4. PMID 10822025. S2CID 40211307.
  5. ^ Alan D. Michelson (31 December 2012). Platelets. Academic Press. pp. 314–. ISBN 978-0-12-387838-0.


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