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ζ-Carotene isomerase (EC 5.2.1.12, Z-ISO, 15-cis-zeta-carotene isomerase) is an enzyme with systematic name 9,15,9'-tricis-zeta-carotene cis-trans-isomerase.[1][2] This enzyme catalyses the following chemical reaction

9,15,9'-tricis-zeta-carotene 9,9'-dicis-zeta-carotene

This enzyme is involved in carotenoid biosynthesis.

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