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MethBase is a database of DNA methylation data derived from next-generation sequencing data.[1] MethBase provides a visualization of publicly available bisulfite sequencing and reduced representation bisulfite sequencing experiments through the UCSC Genome Browser. MethBase contents include single-CpG site resolution methylation levels for each CpG site in the genome of interest, annotation of regions of hypomethylation often associated with gene promoters, and annotation of allele-specific methylation associated with genomic imprinting.

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References

  1. ^ a b Song, Qiang; Decato Benjamin E; Hong Elizabeth; Zhou Meng; Fang Fang; Qu Jianghan; Garvin Tyler; Kessler Michael; Zhou Jun; Smith Andrew D (Dec 2013). "A Reference Methylome Database and Analysis Pipeline to Facilitate Integrative and Comparative Epigenomics". PLOS ONE. 8 (12): e81148. Bibcode:2013PLoSO...881148S. doi:10.1371/journal.pone.0081148. PMC 3855694. PMID 24324667.

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