Black and White Warbler

by | Dec 21, 2017 | Warblers

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Miotine is an anticholinesterase drug. Miotine was the first synthetic carbamate that was used clinically.[1]

Unlike the miotine analog neostigmine, it doesn't have a quaternary ammonium group to give it a permanent positive charge. It can exist as an uncharged free base which could allow it to cross the blood–brain barrier and cause unwanted central nervous system (CNS) side effects.[2]

Miotine equilibrium
Miotine equilibrium

See also

References

  1. ^ "Archived copy" (PDF). Archived from the original (PDF) on 2009-05-09. Retrieved 2008-01-04.{{cite web}}: CS1 maint: archived copy as title (link)
  2. ^ "An introduction to drugs,their action and discovery" (PDF).



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