Maidenhair Spleeenwort – Asplenium trichomanes

by | Dec 9, 2023 | Ferns, NE Native Ferns

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CPD-1 (LS-193743) is a drug with a benzofuranyl piperazine structure, which acts as a potent and selective agonist for the 5-HT2 receptor family, with highest affinity and full agonist efficacy at the 5-HT2C subtype, and lower affinity and partial agonist action at the 5-HT2A and 5-HT2B subtypes.[1][2]

See also

References

  1. ^ Ahmed A, Choo H, Cho YS, Park WK, Pae AN (July 2009). "Identification of novel serotonin 2C receptor ligands by sequential virtual screening". Bioorganic & Medicinal Chemistry. 17 (13): 4559–68. doi:10.1016/j.bmc.2009.05.003. PMID 19464901.
  2. ^ Rodriguez MM, Overshiner C, Leander JD, Li X, Morrow D, Conway RG, et al. (2017). "Behavioral Effects of a Novel Benzofuranyl-Piperazine Serotonin-2C Receptor Agonist Suggest a Potential Therapeutic Application in the Treatment of Obsessive-Compulsive Disorder". Frontiers in Psychiatry. 8: 89. doi:10.3389/fpsyt.2017.00089. PMC 5438973. PMID 28588509.
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