Glabridin is a chemical compound that is found in the root extract of licorice (Glycyrrhiza glabra).[2] Glabridin is an isoflavane, a type of isoflavonoid. This product is part of a larger family of plant-derived molecules, the natural phenols. Glabridin effectively inhibits platelet activation, so it might become therapeutic agent for thromboembolic disorders.[3]
It is used as an ingredient in cosmetics and is listed in International Nomenclature of Cosmetic Ingredients (INCI).
Glabridin is yellowish-brown powder. It is insoluble in water, but soluble in organic solvents such as propylene glycol.
See also
References
- ^ SciFinder Record for CAS#59870-68-7
- ^ Kinoshita T, Kajiyama K, Hiraga Y, Takahashi K, Tamura Y, Mizutani K (1996). "Isoflavan derivatives from Glycyrrhiza glabra (licorice)". Heterocycles. 43 (3): 581–588.
- ^ Chung CL, Chen JH, Huang WC, Sheu JR, Hsia CW, Jayakumar T, Hsia CH, Chiou KR, Hou SM (September 2022). "Glabridin, a Bioactive Flavonoid from Licorice, Effectively Inhibits Platelet Activation in Humans and Mice". International Journal of Molecular Sciences. 23 (19): 11372. doi:10.3390/ijms231911372. PMC 9570097. PMID 36232674.
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